建立基于QuEChERS-气相色谱串联质谱法(GC-MS/MS)快速检测香菇中13种农药残留的分析方法。香菇样品经前处理后，气相色谱分离，多反应离子监测模式(MRM)进行质谱检测，用外标法定量。结果表明，在0.01、0.10、0.50 mg/kg三个添加水平下，回收率范围为75.4%～110.6%。用重复性限反映精密度，均符合标准GB 23200.113—2018的要求。QuEChERS-气相色谱串联质谱法快速、高效、可靠，适用于香菇样品中的农药残留检验检测。

A rapid method for the determination of 13 pesticide residues in Lentinus edodes was established based on QuEChERS-gas chromatography-mass spectrometry(GC-MS/MS). After pretreatment， the Lentinus edodes samples were separated by gas chromatography， detected by mass spectrometry in the multi-reaction ion monitoring mode(MRM)， and quantitatively analyzed with the external standard method. The results showed that the 13 pesticides had good linearity in the range from 0.01 μg/mL to 0.8 μg/mL， and the correlation coefficients R2>0.99. The average recovery ranges were mainly from 75.4% to 110.6% at the three spiked concentration levels(0.01、0.10、0.50 mg/kg). The repeatability limit is used to reflect the precision， which all were accepted the requirements of standard GB 23200.113 — 2018. The method is rapid， efficient and reliable， which is suitable for the detection of pesticide residues in Lentinus edodes samples.

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